Ego is something that's easy to live with because it makes you feel important, but at the same time it can make you lose peace or even feel miserable. If you let ego be your guide, then it's a foregone conclusion that you won't ever find happiness in this world. I think the person with the ego knows it, but breaking that sticky bond by human power alone is usually hopeless.
God, on the other hand, is seemingly not easy to live with and can make you feel uncomfortable too when ego gets in the way. But once you get to know God, he becomes a pure joy and grants you peace and freedom of the heart. You are no longer a slave to your ego, for God can purge it as much as you wish. Again, this is true.